Identification of NPC1 as the target of U18666A, an inhibitor of lysosomal cholesterol export and Ebola infection | eLife
The NPC1 protein: structure implies function - ScienceDirect
NPC1 structure and proposed pathway of cholesterol binding (A)... | Download Scientific Diagram
3.3 Å structure of Niemann–Pick C1 protein reveals insights into the function of the C-terminal luminal domain in cholesterol transport | PNAS
Structure of human Niemann–Pick C1 protein | PNAS
3.3 Å structure of Niemann–Pick C1 protein reveals insights into the function of the C-terminal luminal domain in cholesterol transport | PNAS
IJMS | Free Full-Text | Cholesterol Transport in Wild-Type NPC1 and P691S: Molecular Dynamics Simulations Reveal Changes in Dynamical Behavior
A working model of NPC1/NPC2-mediated LDL-derived cholesterol transport... | Download Scientific Diagram
JCM | Free Full-Text | Molecular Genetics of Niemann–Pick Type C Disease in Italy: An Update on 105 Patients and Description of 18 NPC1 Novel Variants
Figures and data in Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins | eLife
Structural basis for itraconazole-mediated NPC1 inhibition | Nature Communications
Lysosomal cholesterol export reconstituted from fragments of Niemann-Pick C1 | eLife
Guilty until proven innocent: the case of NPC1 and cholesterol: Trends in Biochemical Sciences
Structural basis for itraconazole-mediated NPC1 inhibition | Nature Communications
Structural Insights into the Niemann-Pick C1 (NPC1)-Mediated Cholesterol Transfer and Ebola Infection - ScienceDirect
Cholesterol binding to the sterol-sensing region of Niemann Pick C1 protein confines dynamics of its N-terminal domain | PLOS Computational Biology
Structural basis for itraconazole-mediated NPC1 inhibition | Nature Communications
Schematic representation of the NPC1 protein (not to scale). Cylinders... | Download Scientific Diagram
A working model of NPC1/NPC2-mediated LDL-derived cholesterol transport... | Download Scientific Diagram
Human NPC1: topology, structure, and function. (A) Predicted topology... | Download Scientific Diagram
3.3 Å structure of Niemann–Pick C1 protein reveals insights into the function of the C-terminal luminal domain in cholesterol transport | PNAS
Lysosomal cholesterol export reconstituted from fragments of Niemann-Pick C1 | eLife
Correction of Niemann-Pick type C1 disease with the histone deacetylase inhibitor valproic acid | bioRxiv
Role of the SSD within NPC1 in mediating the binding between NPC1... | Download Scientific Diagram
MARCH6 may contain a sterol sensing domain (A) % similarity of SSDs... | Download Scientific Diagram
IJMS | Free Full-Text | Cholesterol Transport in Wild-Type NPC1 and P691S: Molecular Dynamics Simulations Reveal Changes in Dynamical Behavior
